{"id":17065,"date":"2024-06-19T14:26:07","date_gmt":"2024-06-19T12:26:07","guid":{"rendered":"https:\/\/neurologiaclinica.es\/neurological-diseases-and-disorders\/epileptic-encephalopathy\/"},"modified":"2025-04-28T11:47:59","modified_gmt":"2025-04-28T09:47:59","slug":"epileptic-encephalopathy","status":"publish","type":"page","link":"https:\/\/neurologiaclinica.es\/en\/neurological-diseases-and-disorders\/epileptic-encephalopathy\/","title":{"rendered":"Epileptic encephalopathy"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"17065\" class=\"elementor elementor-17065\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7b77917c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7b77917c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-39b4485b\" data-id=\"39b4485b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5ce7aeb8 elementor-widget elementor-widget-heading\" data-id=\"5ce7aeb8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Epileptic encephalopathy<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6884c49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6884c49\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8e72bbc\" data-id=\"8e72bbc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-557f731 elementor-widget elementor-widget-text-editor\" data-id=\"557f731\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 class=\"wp-block-heading\">Epileptic encephalopathy, definition:<\/h3><p>Epileptic encephalopathy is the name given to a group of <strong>epilepsy syndromes related to cognitive and behavioral disturbances, which begin in the first years of life.<\/strong> These disorders <strong>are differentiated<\/strong> according to the type of epileptic seizures, age of onset, prognosis, response to treatments, etc. They all share difficult-to-control seizures that can impair cognitive and motor functions. Seizures in these patients can be of different types: absence seizures (with disconnection from the environment and little symptomatic expression), tonic seizures (causing stiffness of the muscles of the body, back, arms and legs), but they can also be focal motor, myoclonic or atonic (which can lead to the patient falling).   <\/p><p>Until <strong>2001, the ILAE<\/strong> (International League Against Epilepsy) did not include epileptic encephalopathy in its classification as a distinct category within the diagnosis of epilepsies. In 2010, epileptic encephalopathy was <strong>defined<\/strong> as &#8220;the condition in which the epileptic activity itself contributes to significant cognitive and behavioral disturbances, which are beyond those that the underlying disease alone would cause, and which may worsen over time&#8221;. These alterations would be potentially preventable with the correct treatment of epilepsy (pharmacological, surgical or otherwise).  <\/p><p>Within the epileptic encephalopathies we find:<\/p><ul><li>Early myoclonic encephalopathy.<\/li><li>Rasmussen&#8217;s encephalitis.<\/li><li>Malignant epilepsy with migratory partial seizures in childhood.<\/li><li>Epilepsy with continuous spiral waves of slow sleep.<\/li><li>Myoclonic status in non-progressive encephalopathies.<\/li><li>Dravet syndrome.<\/li><li>Doose syndrome.<\/li><li>Ohtahara syndrome.<\/li><li>Landay-Kleffner syndrome.<\/li><li>West syndrome.<\/li><li>Lennox-Gastaut syndrome.<\/li><li>Unverrich-Lundborg disease<\/li><li>Angelman Syndrome<\/li><li>Prader-Willy syndrome<\/li><li>Rett syndrome<\/li><li>Fragile X syndrome<\/li><li>Others&#8230;<\/li><\/ul><p>In these patients it is<strong> essential<\/strong> to <strong>correctly diagnose the electro-clinical syndrome<\/strong> by means of a complete clinical interview, a physical examination, an exhaustive review of the clinical history and the response to treatments, as well as prolonged video-EEG monitoring (at least 24 hours). High-field neuroimaging (high-resolution magnetic resonance imaging) and brain PET-CT will provide extra information in many cases. In patients in whom a correct diagnosis has not been reached after all the above, an extensive genetic study (specific gene study, epilepsy gene panel, array-CGH or triexome) is necessary, as these tests achieve a definitive diagnosis in about 40-50% of cases. Some genes related to epileptic encephalopathies are SCN1A, SCN2A, SCN8A, ARX, CDKL5, STXBP1, UBE3A, DEPDC5.   <\/p><p>The correct diagnosis, with electroclinical data, neuroimaging, and in some cases genetic testing, will provide prognostic information, and will also help in many cases in the choice of the <strong>correct antiepileptic treatment (pharmacological and\/or surgical)<\/strong>, as well as enabling in some cases participation in <strong>clinical trials with new investigational therapies<\/strong>.<\/p><h3 class=\"wp-block-heading\">TREATMENTS:<\/h3><p>Depending on the type of epileptic encephalopathy, treatment may vary, however in all cases, <strong>early diagnosis and appropriate treatment improves the prognosis<\/strong> of these patients <strong>.<\/strong> <\/p><ol><li>Correct <strong>antiepileptic drugs<\/strong>, selected according to the electroclinical syndrome and underlying cause.<\/li><li><strong>Intravenous immunoglobulin<\/strong>: May be useful in the control of inflammatory phenomena associated with epilepsy and that block inhibitory mechanisms and neuronal excitation.<\/li><li><strong>Ketogenic diet<\/strong>: can be useful in a wide range of epilepsies. This diet should be controlled by a specialized nutritionist. <\/li><li><strong>Experimental treatments<\/strong>: Through clinical trials, for example with fenfluramine or TAK-935 treatments.<\/li><li><strong>Resective or minimally invasive surgery<\/strong> by radiofrequency thermoablation or gamma-knife radiosurgery.<\/li><\/ol><p>Our <a class=\"rank-math-link\" href=\"https:\/\/neurologiaclinica.es\/que-hacemos\/programa-epilepsia\/\">Epilepsy Program<\/a> Team has specialists in epileptic encephalopathy. If you would like to receive information <a class=\"rank-math-link\" href=\"https:\/\/neurologiaclinica.es\/en\/contact\/\">, please contact us<\/a>. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-90643ec elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"90643ec\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b2fb330\" data-id=\"b2fb330\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-18ce360 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"18ce360\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/neurologiaclinica.es\/en\/units\/epilepsy-unit\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-arrow-left\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Go to Epilepsy Unit<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a2685f8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a2685f8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-97041d7\" data-id=\"97041d7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d5ce6b4 elementor-author-box--layout-image-left elementor-author-box--align-center elementor-widget elementor-widget-author-box\" data-id=\"d5ce6b4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"author-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-author-box\">\n\t\t\t\t\t\t\t<a href=\"https:\/\/neurologiaclinica.es\/en\/who-are-we\/medical-equipment\/dr-antonio-gil-nagel-rein\/\" class=\"elementor-author-box__avatar\">\n\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/neurologiaclinica.es\/wp-content\/uploads\/Antonio-Gil-Nagel-1.jpg\" alt=\"Picture of Dr. Antonio Gil-Nagel Rein  \" loading=\"lazy\">\n\t\t\t\t<\/a>\n\t\t\t\n\t\t\t<div class=\"elementor-author-box__text\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/neurologiaclinica.es\/en\/who-are-we\/medical-equipment\/dr-antonio-gil-nagel-rein\/\">\n\t\t\t\t\t\t<h2 class=\"elementor-author-box__name\">\n\t\t\t\t\t\t\tDr. Antonio Gil-Nagel Rein  \t\t\t\t\t\t<\/h2>\n\t\t\t\t\t<\/a>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-author-box__bio\">\n\t\t\t\t\t\t<p>Date of issue: 04\/06\/2019<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ee46975 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"ee46975\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/neurologiaclinica.es\/en\/neurological-diseases-and-disorders\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-arrow-left\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Go to List of neurological diseases and disorders<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ea2e39b 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M9.5,20.4c0.6,0,1-0.5,1-1c0-0.6-0.5-1-1-1c-0.6,0-1,0.5-1,1C8.4,19.9,8.9,20.4,9.5,20.4z\"><\/path>\t<\/g><\/g><\/svg>\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<a href=\"https:\/\/www.neurologiaclinica.es\/quienes-somos\/#b2\" >\n\t\t\t\t\t\t\tSpecialists\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tMeet our extensive team\n\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-5e08430 animated-slow elementor-invisible\" data-id=\"5e08430\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;fadeInDown&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t<div 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type=\"text\/css\">\t.st0{fill:#007399;}<\/style><path class=\"st0\" d=\"M2.7,14.1c0-6.3,5.1-11.4,11.4-11.4s11.5,5.1,11.5,11.4s-5.2,11.5-11.5,11.5S2.7,20.5,2.7,14.1z M14.1,3.2 C8.1,3.3,3.3,8,3.2,14C3.2,20.2,8,25,14,25.1c6.1,0.1,11-4.8,11-10.8C25.1,8.1,20.2,3.3,14.1,3.2z\"><\/path><path class=\"st0\" d=\"M19.5,12.9c0-0.4-0.2-0.6-0.6-0.6c-0.8,0-1.6,0-2.4,0c-0.3,0-0.3,0-0.3-0.3c0-0.8,0-1.6,0-2.4 c0-0.5-0.1-0.7-0.7-0.7c-0.5,0-1,0-1.4,0c-0.5,0-1,0-1.5,0c-0.5,0-0.6,0.2-0.6,0.6c0,0.8,0,1.6,0,2.4c0,0.2,0,0.2-0.2,0.2 c-0.8,0-1.6,0-2.4,0c-0.5,0-0.6,0.2-0.6,0.6c0,1,0,2,0,2.9c0,0.5,0.2,0.6,0.6,0.6c0.8,0,1.6,0,2.4,0c0.2,0,0.2,0,0.2,0.2 c0,0.8,0,1.6,0,2.4c0,0.5,0.2,0.6,0.6,0.6c1,0,2,0,2.9,0c0.5,0,0.6-0.2,0.6-0.6c0-0.8,0-1.6,0-2.4c0-0.3,0-0.3,0.3-0.3l2.4,0 c0.4,0,0.6-0.2,0.6-0.6C19.5,14.8,19.5,13.9,19.5,12.9z\"><\/path><\/svg>\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<a 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class=\"st0\" d=\"M16.7,20.7c-0.5-0.1-1-0.2-1.4-0.4c-1.2-0.4-2.2-1.1-3.2-1.9c-1.1-0.9-2.1-2-2.9-3.2   c-0.6-0.9-1.1-1.8-1.3-2.9c0-0.2-0.1-0.3-0.1-0.5c0-0.2,0-0.3,0.1-0.5c0.4-0.6,0.9-1.2,1.4-1.8c0.2-0.2,0.4-0.4,0.6-0.6   c0.3-0.2,0.4-0.2,0.6,0.1c0.3,0.3,0.5,0.6,0.7,1c0.3,0.5,0.6,1,0.9,1.6c0.2,0.4,0.2,0.5-0.2,0.8c-0.3,0.2-0.5,0.4-0.8,0.7   c-0.1,0.1-0.1,0.1-0.1,0.3c0.2,0.8,0.6,1.5,1.2,2.1c0.7,0.8,1.5,1.4,2.5,1.8c0.1,0,0.1,0,0.2,0.1c0.3,0.1,0.3,0.1,0.6-0.2   c0.2-0.2,0.3-0.4,0.5-0.6c0,0,0,0,0.1-0.1c0.3-0.3,0.4-0.3,0.8-0.2c0.6,0.2,1.1,0.6,1.6,0.9c0.3,0.2,0.6,0.4,0.8,0.6   c0.4,0.3,0.4,0.5,0.1,0.9c-0.4,0.5-0.9,0.9-1.4,1.2c-0.3,0.2-0.6,0.5-0.9,0.6C16.9,20.7,16.8,20.8,16.7,20.7z\"><\/path>\t\t<path class=\"st0\" d=\"M19.1,14.4c-0.1,0-0.2,0-0.3,0c-0.1,0-0.1,0-0.1-0.1c0-0.3,0-0.6-0.1-1c-0.4-1.8-2-3.3-3.9-3.5   c-0.2,0-0.3,0-0.5,0c-0.1,0-0.1,0-0.1-0.1c0-0.2,0-0.4,0-0.6c0-0.1,0-0.1,0.1-0.1c0.7,0,1.4,0.1,2,0.4c1.8,0.8,2.9,2.1,3.3,4   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us\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-23d6abf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"23d6abf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-40d99db\" data-id=\"40d99db\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7191002 elementor-widget elementor-widget-spacer\" data-id=\"7191002\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-02c72a5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"02c72a5\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a6c6dd5\" data-id=\"a6c6dd5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-325b4e9 elementor-widget elementor-widget-heading\" data-id=\"325b4e9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">GET INFO:<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-84cc5d5 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"84cc5d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/www.neurologiaclinica.es\/neurologos-en-madrid\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">About our Programs, Units and Treatments<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Epileptic encephalopathy, definition: Epileptic encephalopathy is the name given to a group of epilepsy syndromes related to cognitive and behavioral disturbances, which begin in the first years of life. These disorders are differentiated according to the type of epileptic seizures, age of onset, prognosis, response to treatments, etc. They all share difficult-to-control seizures that can [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":16398,"parent":16593,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-17065","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/pages\/17065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/comments?post=17065"}],"version-history":[{"count":5,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/pages\/17065\/revisions"}],"predecessor-version":[{"id":17889,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/pages\/17065\/revisions\/17889"}],"up":[{"embeddable":true,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/pages\/16593"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/media\/16398"}],"wp:attachment":[{"href":"https:\/\/neurologiaclinica.es\/en\/wp-json\/wp\/v2\/media?parent=17065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}